Coreg | Carvedilol Tablet Breastfeeding

It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Coreg | Carvedilol Tablet is safe for baby while breastfed.

What is Coreg | Carvedilol Tablet used for?


COREG is an alpha/beta-adrenergic blocking agent indicated for the treatment of: Mild to severe chronic heart failure (1.1) Left ventricular dysfunction following myocardial infarction in clinically stable patients (1.2) Hypertension (1.3) 1.1 Heart Failure COREG is indicated for the treatment of mild-to-severe chronic heart failure of ischemic or cardiomyopathic origin, usually in addition to diuretics, ACE inhibitors, and digitalis, to increase survival and, also, to reduce the risk of hospitalization [see Drug Interactions (7.4) and Clinical Studies (14.1)]. 1.2 Left Ventricular Dysfunction Following Myocardial Infarction COREG is indicated to reduce cardiovascular mortality in clinically stable patients who have survived the acute phase of a myocardial infarction and have a left ventricular ejection fraction of ≤40% (with or without symptomatic heart failure) [see Clinical Studies (14.2)]. 1.3 Hypertension COREG is indicated for the management of essential hypertension [see Clinical Studies (14.3, 14.4)]. It can be used alone or in combination with other antihypertensive agents, especially thiazide-type diuretics [see Drug Interactions (7.2)].

I am breastfeeding mother and I am using Coreg | Carvedilol Tablet. Can it have any bad effect on my kid? Shall I search for better alternative?

Coreg | Carvedilol Tablet low risk for breastfeeding
Coreg | Carvedilol Tablet contains only one active ingredient that is Carvedilol. We have analyzed the usage of Carvedilol in breastfeeding and our analysis suggest that Carvedilol poses Low risk for infant while breastfeeding and hence Coreg | Carvedilol Tablet itself shall be considered Low risk item for breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known whether this drug is excreted in human milk. Studies in rats have shown that carvedilol and/or its metabolites (as well as other β-blockers) cross the placental barrier and are excreted in breast milk. There was increased mortality at one week post-partum in neonates from rats treated with 60 mg/kg/day (10 times the MRHD as mg/m2) and above during the last trimester through day 22 of lactation. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from β-blockers, especially bradycardia, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. The effects of other α- and β-blocking agents have included perinatal and neonatal distress.

Coreg | Carvedilol Tablet Breastfeeding Analsys


Carvedilol while Breastfeeding

Low Risk

CAS Number: 72956-09-3

Since the last update we have not found published data on its excretion in breast milk. Its high percentage of plasma protein binding makes excretion in significant amounts very unlikely (Riant 1986). Other adrenergic beta-blockers of the same family and similar chemical structure are compatible with breastfeeding (see specific information for Labetalol or Propranolol). Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity.

Coreg | Carvedilol Tablet Breastfeeding Analsys - 2


Carvedilol while Breastfeeding

CAS Number: 72956-09-3

Based on its physicochemical properties, carvedilol appears to present a low-risk to the breastfed infant. Because there is no published experience with carvedilol during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

Coreg | Carvedilol Tablet and breastfeeding

What should I do if already breastfed my kid after using Coreg | Carvedilol Tablet?

Coreg | Carvedilol Tablet is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Coreg | Carvedilol Tablet so you should inform him based on your convenience.


I am nursing mother and my doctor has suggested me to use Coreg | Carvedilol Tablet, is it safe?

Though Coreg | Carvedilol Tablet dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Coreg | Carvedilol Tablet, will my baby need extra monitoring?

Not much monitoring required while using Coreg | Carvedilol Tablet


Who can I talk to if I have questions about usage of Coreg | Carvedilol Tablet in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week