Terbinafine Hcl Chlortimazole And Tolnaftate | Terbinafine Hcl, Clotrimazole, Tolnaftate Solution while Breastfeeding

What is Terbinafine Hcl Chlortimazole And Tolnaftate | Terbinafine Hcl, Clotrimazole, Tolnaftate Solution ?

Can I use Terbinafine Hcl Chlortimazole And Tolnaftate | Terbinafine Hcl, Clotrimazole, Tolnaftate Solution while breastfeeding?

Terbinafine while Breastfeeding

CAS Number: 91161-71-6

Pharmacokinetics data (low oral bioavailability, high volume of distribution and high protein-binding capacity) explains the scanty excretion into breast milk observed in nursing mothers who received this medication. In addition, a poor oral absorption would make even more difficult any pass of this drug through ingested milk to the infant's blood, except in newborns or premature who would show a higher intestinal absorption. Avoid using in prematures who are under treatment with caffeine or theophylline because terbinafine alters its metabolic degradation and increases plasma concentration. Since topical absorption is less than 1%, a significant excretion into breast milk after application on skin is not expected. Do not use on the breast to prevent ingestion by the infant, otherwise apply after a meal and wipe it out thoroughly with water before next feeding. It is recommended to avoid using on the nipple creams, gels and other products intended for use on skin that may contain paraffin (mineral oil) in order to keep from absorption the infant.

Clotrimazole while Breastfeeding

CAS Number: 23593-75-1

Excretion into breast milk is very unlikely since absorption through skin, vaginal mucosa, and, even intestinal mucosa into plasma is very poor with non-significant plasma levels or below the detection threshold (<10 ng/mL). In addition, because of a high plasma protein binding capacity, excretion into breast milk seems to be less likely. It is used frequently for treatment of Candida infection, either in skin or mouth mucosa, even in newborn and premature infants without observed side-effects. In case of use on the nipple, do it after feeding the baby and cleanse thoroughly the surface before the next one. Do not use creams, gels and other locally applied products that contain paraffin (mineral oil) to prevent absorption by the infant.

Terbinafine while Breastfeeding

CAS Number: 91161-71-6

Limited information indicates that oral maternal doses of 500 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. Monitor the infant for jaundice or other signs of liver toxicity, especially in younger, exclusively breastfed infants. Some sources recommend avoiding oral terbinafine during nursing.[1] Topical terbinafine has not been studied during breastfeeding. Because only about 1% is absorbed after topical application, it is considered a low risk to the nursing infant.[1][2] Avoid application to the nipple area and ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream, gel or liquid products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]

Clotrimazole while Breastfeeding

CAS Number: 23593-75-1

Because clotrimazole has poor oral bioavailability, it is unlikely to adversely affect the breastfed infant, including topical application to the nipples. It has been used orally in infants with thrush, sometimes successfully after nystatin has failed.[1] Any excess cream or ointment should be removed from the nipples before nursing. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Tolnaftate while Breastfeeding

CAS Number: 2398-96-1

Topical tolnaftate has not been studied during breastfeeding and no data are available on the extent of its absorption after topical application. Because it is probably poorly absorbed after topical application, it is considered a low risk to the nursing infant. Avoid application to the nipple area and ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream, gel or liquid products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1]

Tolnaftate and Breastfeeding

I already used Terbinafine Hcl Chlortimazole And Tolnaftate | Terbinafine Hcl, Clotrimazole, Tolnaftate Solution and meanwhile I breastfed my baby should I be concerned?

My doctor has prescribed me Terbinafine Hcl Chlortimazole And Tolnaftate | Terbinafine Hcl, Clotrimazole, Tolnaftate Solution, what should I do?

If I am using Terbinafine Hcl Chlortimazole And Tolnaftate | Terbinafine Hcl, Clotrimazole, Tolnaftate Solution, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Terbinafine Hcl Chlortimazole And Tolnaftate | Terbinafine Hcl, Clotrimazole, Tolnaftate Solution in breastfeeding?