Breast milk is superior in nutrition, It provides resistance against infections and allergies, It is naturally sterile. Despite all the advantages of breastfeeding some mothers choose to pause the breastfeeding in fear of harmful effects of medicines passing in breast milk. Are you wondering about breastfeeding and using Phenytoin Er | Phenytoin Sodium Capsule ? Know what is Phenytoin Er | Phenytoin Sodium Capsule and how it can affect your breast milk and whether Phenytoin Er | Phenytoin Sodium Capsule is safe for your kid or not.
Phenytoin sodium is an antiepileptic drug. Phenytoin sodium is related to the barbiturates in chemical structure, but has a five-membered ring. The chemical name is 5,5-Diphenylhydantoin sodium salt, having a molecular weight of 274.25 and having the following structural formula and molecular formula: Each extended phenytoin sodium capsule, USP, for oral administration, contains 100 mg phenytoin sodium, USP. Each capsule also contains the following inactive ingredients: colloidal silicon dioxide, hydroxyethyl cellulose, magnesium oxide, magnesium stearate, microcrystalline cellulose, povidone and sodium lauryl sulfate. In addition, each of the empty gelatin capsules contains the following: D and C Red No. 28, D and C Red No. 33, FD and C Blue No. 1, gelatin, sodium lauryl sulfate and titanium dioxide. The imprinting ink contains the following: black iron oxide, D and C Yellow No. 10 Aluminum Lake, FD and C Blue No. 1 Aluminum Lake, FD and C Blue No. 2 Aluminum Lake, FD and C Red No. 40 Aluminum Lake, propylene glycol and shellac glaze. Product in vivo performance is characterized by a slow and extended rate of absorption with peak blood concentrations expected in 4 to 12 hours as contrasted to prompt phenytoin sodium capsules, USP with a rapid rate of absorption with peak blood concentration expected in 11⁄2 to 3 hours. Extended phenytoin sodium capsules, USP 100 mg meet USP Dissolution Test 2. STRUCTURE IMAGE
What are the risk associated with Phenytoin Er | Phenytoin Sodium Capsule usage while breastfeeding? What precautions shall I take while using it in breastfeeding?
Active ingredient in Phenytoin Er | Phenytoin Sodium Capsule is Phenytoin sodium and based on our analysis of Phenytoin sodium it appears that using Phenytoin Er | Phenytoin Sodium Capsule is safe in breastfeeding. Below is analysis of Phenytoin sodium while breastfeeding.
Phenytoin Er | Phenytoin Sodium Capsule Breastfeeding Analsys
SafeCAS Number: 57-41-0
Type IB antiarrhythmic agent and anticonvulsant drug. It is excreted into breast milk in clinically non-significant amount and no problems have appeared on clinical follow up, and, long-term psychomotor development in infants whose mothers received this treatment, except in some isolated cases of patients who were on anticonvulsant polytherapy.Plasma levels in these infants were undetectable or very low. It may appear a withdrawal syndrome with hyperexcitability after abruptly stopping breastfeeding. It has been authorized for use in infants and newborns. American Academy of Pediatrics states that it is usually compatible with breastfeeding medication.WHO List of Essential Medicines 2002: compatible with breastfeeding.
Phenytoin Er | Phenytoin Sodium Capsule Breastfeeding Analsys - 2
CAS Number: 57-41-0
Breastfeeding during phenytoin monotherapy does not appear to adversely affect infant growth or development, and breastfed infants had higher IQs and enhanced verbal abilities than nonbreastfed infants at 6 years of age in one study.[1] If phenytoin is required by the mother, it is not necessarily a reason to discontinue breastfeeding. Because of the low levels of phenytoin in breastmilk, amounts ingested by the infant are small and usually cause no difficulties in breastfed infants when used alone except for rare idiosyncratic reactions. Combination therapy with sedating anticonvulsants or psychotropics may result in infant sedation or withdrawal reactions. In one case report, maternal phenytoin dosage requirements decreased as breastfeeding was discontinued.[2]
What if I already have used Phenytoin Er | Phenytoin Sodium Capsule?
As usage of Phenytoin Er | Phenytoin Sodium Capsule is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Phenytoin Er | Phenytoin Sodium Capsule else no further action is required.
I am nursing mother and my doctor has suggested me to use Phenytoin Er | Phenytoin Sodium Capsule, is it safe?
Definitely, Phenytoin Er | Phenytoin Sodium Capsule is safe in lactation for baby. No wonder your doctor has recommended it.
If I am using Phenytoin Er | Phenytoin Sodium Capsule, will my baby need extra monitoring?
No extra baby monitoring required while mother is using Phenytoin Er | Phenytoin Sodium Capsule
Who can I talk to if I have questions about usage of Phenytoin Er | Phenytoin Sodium Capsule in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week