Diovan Hct | Hydrochlorothiazide, Valsartan Tablet Breastfeeding
Nutrients from the food that you eat passes to your breast milk. Its good idea to take healthy diet while breastfeeding. You may need to consume more calories per day to support healthy body system. Some time it gets necessary take medicine while you are breastfeeding and as other food items passes into breast milk, medicine passes as well hence it becomes obvious to understand its effects while breastfeeding. We have analyzed many medications and in this sheet we will present some fact and known information associated with Diovan Hct | Hydrochlorothiazide, Valsartan Tablet while breast-feeding.

What is Diovan Hct | Hydrochlorothiazide, Valsartan Tablet used for?


Diovan HCT (valsartan and hydrochlorothiazide, USP) is indicated for the treatment of hypertension. Diovan HCT may be used in patients whose blood pressure is not adequately controlled on monotherapy. Diovan HCT may be used as initial therapy in patients who are likely to need multiple drugs to achieve blood pressure goals. The choice of Diovan HCT as initial therapy for hypertension should be based on an assessment of potential benefits and risks. Patients with stage 2 hypertension are at a relatively high risk for cardiovascular events (such as strokes, heart attacks, and heart failure), kidney failure, and vision problems, so prompt treatment is clinically relevant. The decision to use a combination as initial therapy should be individualized and should be shaped by considerations such as baseline blood pressure, the target goal and the incremental likelihood of achieving goal with a combination compared to monotherapy. Individual blood pressure goals may vary based upon the patient’s risk. Data from the high dose multifactorial trial [See Clinical Studies (14.1)] provides estimates of the probability of reaching a target blood pressure with Diovan HCT compared to valsartan or hydrochlorothiazide monotherapy. The figures below provide estimates of the likelihood of achieving systolic or diastolic blood pressure control with Diovan HCT 320/25 mg, based upon baseline systolic or diastolic blood pressure. The curve of each treatment group was estimated by logistic regression modeling. The estimated likelihood at the right tail of each curve is less reliable due to small numbers of subjects with high baseline blood pressures. For example, a patient with a baseline blood pressure of 160/100 mmHg has about a 41% likelihood of achieving a goal of less than 140 mmHg (systolic) and 60% likelihood of achieving less than 90 mmHg (diastolic) on valsartan alone and the likelihood of achieving these goals on HCTZ alone is about 50% (systolic) or 57% (diastolic). The likelihood of achieving these goals on Diovan HCT rises to about 84% (systolic) or 80% (diastolic). The likelihood of achieving these goals on placebo is about 23% (systolic) or 36% (diastolic). CHARTS

Is using Diovan Hct | Hydrochlorothiazide, Valsartan Tablet unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?

Diovan Hct | Hydrochlorothiazide, Valsartan Tablet low risk for breastfeeding
Hydrochlorothiazide and Valsartan are the two main ingredients of Diovan Hct | Hydrochlorothiazide, Valsartan Tablet. Based on our individual analysis of Hydrochlorothiazide and Valsartan we can safely say that Diovan Hct | Hydrochlorothiazide, Valsartan Tablet has low risk while breastfeeding. Below we have summarized the usage of Hydrochlorothiazide and Valsartan while breastfeeding, we recommend you to go through it for better understanding of your usage.

Diovan Hct | Hydrochlorothiazide, Valsartan Tablet Breastfeeding Analsys


Hydrochlorothiazide while Breastfeeding

Safe

CAS Number: 58-93-5

Thiazide diuretic drug. Excretion into breast milk is clinically non-significant. No side-effects were observed in a one-month old breastfed baby whose mother was treated with this medication. Drug level in the plasma of this child was undetectable. Long-term treatment with diuretic drugs (particularly Thiazide type ones with long-lasting effect and loop-acting mechanism) may inhibit lactation, mostly if lactation is not well-established yet. Use as lower dose as possible, especially during the first postnatal month. American Academy of Pediatrics 2013: Maternal Medication Usually Compatible With Breastfeeding. WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Valsartan while Breastfeeding

Low Risk

CAS Number: 137862-53-4

At latest update, relevant published data on excretion into breast milk were not found. A high protein-binding capacity makes excretion into breast milk unlikely. In addition, a low oral bioavailability makes difficult the absorption towards the infant's plasma from ingested milk, except in prematures or newborns who may show an increased absorption. Case report of kidney function impairment of a baby whose mother had taken Telmisartan in pregnancy. Until more data on this medication is available, safer alternative drugs are preferred, especially in premature babies or during the neonatal period. Should an ARA-II medication (Sartan type) be necessary, the associated risk may be decreased by choosing the one with a favorable pharmacokinetics (shorter half-life elimination time and lower bioavailability) like Eprosartan and Losartan


Diovan Hct | Hydrochlorothiazide, Valsartan Tablet Breastfeeding Analsys - 2


Hydrochlorothiazide while Breastfeeding

CAS Number: 58-93-5

Hydrochlorothiazide doses of 50 mg daily or less are acceptable during lactation. Intense diuresis with large doses may decrease breastmilk production.

Valsartan while Breastfeeding

CAS Number: 137862-53-4

Because no information is available on the use of valsartan during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.



I am nursing mother and I have already used Diovan Hct | Hydrochlorothiazide, Valsartan Tablet, what should I do?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Diovan Hct | Hydrochlorothiazide, Valsartan Tablet then you shall inform your doctor, But you should not be worried too much as Diovan Hct | Hydrochlorothiazide, Valsartan Tablet comes in category of low risk drug.


My health care provider has asked me to use Diovan Hct | Hydrochlorothiazide, Valsartan Tablet, what to do?

Diovan Hct | Hydrochlorothiazide, Valsartan Tablet comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Diovan Hct | Hydrochlorothiazide, Valsartan Tablet, will my baby need extra monitoring?

Not much


Who can I talk to if I have questions about usage of Diovan Hct | Hydrochlorothiazide, Valsartan Tablet in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

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