Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Glimepiride Tablet is safe in breast-feeding or not.
What is Glimepiride Tablet used for?
Glimepiride tablets USP are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [see Clinical Studies ( 14.1) ] . Glimepiride is a sulfonylurea indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus ( 1.1). Important Limitations of Use: Not for treating type 1 diabetes mellitus or diabetic ketoacidosis ( 1.1). 1.1 Important Limitations of Use Glimepiride tablets USP should not be used for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis, as it would not be effective in these settings.
Is Glimepiride Tablet usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?
As Glimepiride Tablet is made of only Glimepiride, and Glimepiride is unsafe to use in breastfeeding we can safely reach on conclusion that Glimepiride Tablet is also unsafe to use while breastfeeding. Below is detailed analysis of Glimepiride and Glimepiride Tablet during location. We recommend you to go through provided detailed analysis as below take decision accordingly. We also recommend you talk to your health care provider before making final decision.
Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known whether glimepiride is excreted in human milk. During pre- and post-natal studies in rats, significant concentrations of glimepiride were present in breast milk and the serum of the pups. Offspring of rats exposed to high levels of glimepiride during pregnancy and lactation developed skeletal deformities consisting of shortening, thickening, and bending of the humerus during the postnatal period. These skeletal deformations were determined to be the result of nursing from mothers exposed to glimepiride. Based on these animal data and the potential for hypoglycemia in a nursing infant, a decision should be made whether to discontinue nursing or discontinue glimepiride, taking into account the importance of glimepiride to the mother.
Glimepiride Tablet Breastfeeding Analsys
CAS Number: 93479-97-1
Sulfonilurea drugs stimulate secretion of endogen insulin. Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus
Glimepiride Tablet Breastfeeding Analsys - 2
CAS Number: 93479-97-1
Because no information is available on the use of glimepiride during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. Monitor breastfed infants for signs of hypoglycemia such as jitteriness, excessive sleepiness, poor feeding, seizures cyanosis, apnea, or hypothermia. If there is concern, monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with glimepiride.
I am nursing mother and I have already used Glimepiride Tablet, what should I do?
We have already established that Glimepiride Tablet is unsafe in breastfeeding and breastfeeding while using Glimepiride Tablet is not a good idea however if have already used and then breastfed the baby then you shall monitor the behavior and health of baby closely and inform your doctor as soon as possible. In case of emergency please call 911.
I am nursing mother and my doctor has suggested me to use Glimepiride Tablet, is it safe?
If your doctor knows that you are breastfeeding mother and still prescribes Glimepiride Tablet then there must be good reason for that as Glimepiride Tablet is considered unsafe, It usually happens when doctor finds that overall advantage of taking outweighs the overall risk.
If I am using Glimepiride Tablet, will my baby need extra monitoring?
Yes, Extra monitoring is required if mother is using Glimepiride Tablet and breastfeeding as it is considered unsafe for baby.
Who can I talk to if I have questions about usage of Glimepiride Tablet in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week