Chlorpheniramine Maleate, Phenylephrine Hydrochloride while Breastfeeding

What is Chlorpheniramine Maleate, Phenylephrine Hydrochloride used for?

Is Chlorpheniramine Maleate, Phenylephrine Hydrochloride safe to use while breastfeeding? Can it interfere with growth and development of my kid?

Chlorpheniramine maleate while Breastfeeding

CAS Number: 132-22-9

First generation antihistaminic and alchylamine drug, with sedative effect. Its active isomer is Dexchlorfeniramine. Likely inhibition of lactation within the first weeks post delivery because anti-prolactin effect.. Short-term and low dose (2 mg one or twice-day) treatment is compatible with breastfeeding. Be aware of somnolence in the child. For long-term treatment an alternative drug should be preferred. Compounds in association with expectorants, corticoids and cough relief medicines are available. Avoid drug associations especially while breastfeeding. Follow-up for sedation and feeding ability of the infant. Bed-sharing is not recommended for mothers who are taking this medication.

Phenylephrine hydrochloride while Breastfeeding

CAS Number: 59-42-7

Used on topical decongestant solutions for nose drops at low concentration. 10% midriatic eye drops are available. Because low concentration is used on nose and ophtalmic drops a significant excretion into breast milk is unlikely. Low oral biodisponibility minimizes any risk of harmful effect in the infant. Authorized for nasal or ophtalmic use on children aged younger than 1 year. Although on latest update relevant data on breastfeeding was not found it is considered to be safe when minimal dose is used. Avoid excessive or long term use. A related drug Pseudoephedrine can inhibit milk production. It would be advisable to press on the lachrimal sac to minimize absorption.

Chlorpheniramine maleate while Breastfeeding

CAS Number: 132-22-9

Small (2 to 4 mg), occasional doses of chlorpheniramine are acceptable during breastfeeding. Larger doses or more prolonged use might cause effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as spseudoephedrine or before lactation is well established. Single bedtime doses after the last feeding of the day may be adequate for many women and will minimize any effects of the drug. The nonsedating antihistamines are preferred alternatives, though.

Phenylephrine hydrochloride while Breastfeeding

CAS Number: 59-42-7

The oral bioavailability of phenylephrine is only about 40%,[1] so the drug is unlikely to reach the infant in large amounts. However, intravenous or oral administration of phenylephrine might decrease milk production. Because no information is available on the use of oral phenylephrine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.Phenylephrine nasal spray or ophthalmic drops are less likely to decrease lactation. To substantially diminish the effect of the drug after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

What if I already have used Chlorpheniramine Maleate, Phenylephrine Hydrochloride?

My health care provider has asked me to use Chlorpheniramine Maleate, Phenylephrine Hydrochloride, what to do?

If I am using Chlorpheniramine Maleate, Phenylephrine Hydrochloride, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Chlorpheniramine Maleate, Phenylephrine Hydrochloride in breastfeeding?