Nutrients from the food that you eat passes to your breast milk. Its good idea to take healthy diet while breastfeeding. You may need to consume more calories per day to support healthy body system. Some time it gets necessary take medicine while you are breastfeeding and as other food items passes into breast milk, medicine passes as well hence it becomes obvious to understand its effects while breastfeeding. We have analyzed many medications and in this sheet we will present some fact and known information associated with Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution while breast-feeding.
What is Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution ?
Cathflo® Activase® (Alteplase) is indicated for the restoration of function to central venous access devices as assessed by the ability to withdraw blood.
Is using Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution safe or dangerous while breastfeeding?
Alteplase is the only one ingredient used in manufacturing of Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution, Which makes it easier to analyze its effect in breastfeeding. As per our analysis of Alteplase it is safe to use Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution while lactating. We suggest you to check further details below about Alteplase usage in breastfeeding.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers It is not known whether Cathflo Activase is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Cathflo Activase is administered to a nursing woman.
Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution Breastfeeding Analsys
SafeCAS Number: 105857-23-6
Synthetic recombinant protein formed by a sequence of amino acids that are identical to Human Tissue Plasminogen Activator (t-PA) which is found in colostrum and mature milk. A rapid metabolic rate and high molecular weight explains a less than probable excretion into breast milk. Even more, protein structure would impede gut absorption in the child with exception of the first post-partum week.
Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution Breastfeeding Analsys - 2
CAS Number: 105857-23-6
Tissue plasminogen activator (tPA), which is identical to alteplase, is a normal component of human colostrum and breastmilk.[1][2][3] Levels in milk are highest in colostrum and decrease rapidly during the first week, followed by a sower decrease over time.[2][3] Because alteplase is a large protein molecule with a molecular weight of about 59,000, absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. No information is available on the clinical use of alteplase during breastfeeding. Until more data become available, alteplase should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
I am nursing mother and I have already used Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution, what should I do?
As usage of Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution else no further action is required.
My doctor has prescribed me Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution, what should I do?
Usage of Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution is safe for nursing mothers and baby, No worries.
If I am using Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution, will my baby need extra monitoring?
No
Who can I talk to if I have questions about usage of Cathflo Activase | Alteplase Injection, Powder, Lyophilized, For Solution in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week