Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule Breastfeeding
For most of the drugs advantages of taking medications overweighs the potential risks however some drugs could be really dangerous for breastfed baby hence every medication shall be considered separately. In this page we will discuss about purpose of Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule and its risk associated with lactation. We will also discuss the usage of Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule and some common side effects associated with Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule.

What is Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule ?


Divalproex sodium delayed release capsules are an anti-epileptic drug indicated for: Monotherapy and adjunctive therapy of complex partial seizures and simple and complex absence seizures; adjunctive therapy in patients with multiple seizure types that include absence seizures (1) 1.1 Epilepsy Divalproex sodium delayed release capsules are indicated as monotherapy and adjunctive therapy in the treatment of adult patients and pediatric patients down to the age of 10 years with complex partial seizures that occur either in isolation or in association with other types of seizures. Divalproex sodium delayed release capsules are also indicated for use as sole and adjunctive therapy in the treatment of simple and complex absence seizures, and adjunctively in patients with multiple seizure types that include absence seizures. Simple absence is defined as very brief clouding of the sensorium or loss of consciousness accompanied by certain generalized epileptic discharges without other detectable clinical signs. Complex absence is the term used when other signs are also present. 1.2 Important Limitations Because of the risk to the fetus of decreased IQ, neurodevelopmental disorders, neural tube defects, and other major congenital malformations, which may occur very early in pregnancy, valproate should not be used to treat women with epilepsy or bipolar disorder who are pregnant or who plan to become pregnant unless other medications have failed to provide adequate symptom control or are otherwise unacceptable. Valproate should not be administered to a woman of childbearing potential unless other medications have failed to provide adequate symptom control or are otherwise unacceptable [see Warnings and Precautions (5.2, 5.3, 5.4), Use in Specific Populations (8.1), and Patient Counseling Information (17)]. For prophylaxis of migraine headaches, valproate is contraindicated in women who are pregnant and in women of childbearing potential who are not using effective contraception [see Contraindications (4)] .
1.1 Epilepsy Divalproex sodium delayed release capsules are indicated as monotherapy and adjunctive therapy in the treatment of adult patients and pediatric patients down to the age of 10 years with complex partial seizures that occur either in isolation or in association with other types of seizures. Divalproex sodium delayed release capsules are also indicated for use as sole and adjunctive therapy in the treatment of simple and complex absence seizures, and adjunctively in patients with multiple seizure types that include absence seizures. Simple absence is defined as very brief clouding of the sensorium or loss of consciousness accompanied by certain generalized epileptic discharges without other detectable clinical signs. Complex absence is the term used when other signs are also present.
1.2 Important Limitations Because of the risk to the fetus of decreased IQ, neurodevelopmental disorders, neural tube defects, and other major congenital malformations, which may occur very early in pregnancy, valproate should not be used to treat women with epilepsy or bipolar disorder who are pregnant or who plan to become pregnant unless other medications have failed to provide adequate symptom control or are otherwise unacceptable. Valproate should not be administered to a woman of childbearing potential unless other medications have failed to provide adequate symptom control or are otherwise unacceptable [see Warnings and Precautions (5.2, 5.3, 5.4), Use in Specific Populations (8.1), and Patient Counseling Information (17)]. For prophylaxis of migraine headaches, valproate is contraindicated in women who are pregnant and in women of childbearing potential who are not using effective contraception [see Contraindications (4)] .

Is using Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule safe or dangerous while breastfeeding?

Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule safe for breastfeeding
Active ingredient in Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule is Valproic acid and based on our analysis of Valproic acid it appears that using Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule is safe in breastfeeding. Below is analysis of Valproic acid while breastfeeding.

Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule Breastfeeding Analsys


Valproic acid while Breastfeeding

Safe

CAS Number: 99-66-1

It is excreted in breast milk in clinically non-significant amount without problems in the short or long term in infants whose mothers were treated. Plasma levels of these infants were undetectable or very low. Cognitive development did not suffer any alteration. An infant was presented with thrombocytopenic purpura and anemia who recovered after removing valproate in the mother. However, doubts were raised on whether it was instead a post-viral reaction that led to idiopathic thrombocytopenic purpura. The administration of valproic acid does not affect prolactin levels. The American Academy of Pediatrics rates it as usual compatible with breastfeeding medication.WHO List of Essential Medicines 2002: compatible with breastfeeding.


Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule Breastfeeding Analsys - 2


Valproic acid while Breastfeeding

CAS Number: 99-66-1

Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule and breastfeeding

Breastfeeding during valproic acid monotherapy does not appear to adversely affect infant growth or development, and breastfed infants had higher IQs and enhanced verbal abilities than nonbreastfed infants at 6 years of age in one study.[1] If valproic acid is required by the mother, it is not necessarily a reason to discontinue breastfeeding. Because of the low levels of valproic acid in breastmilk and infant serum, no definite adverse reactions to valproic acid during breastfeeding have been reported. Theoretically, breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy. A questionable case of thrombocytopenia has been reported, so monitor the infant for unusual bruising or bleeding. One author recommends monitoring infant serum valproate levels, platelets and liver enzymes during therapy.[1] Combination therapy with sedating anticonvulsants or psychotropics may result in infant sedation or withdrawal reactions.


Is Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule safe while breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule?

Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule is safe in breastfeeding and should not create any health problem for your baby but in case you feel any health issue associated with Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule you should contact your doctor or health care provider. Be it pregnancy or lactation you shall keep your doctor informed.


My doctor has prescribed me Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule, what should I do?

Definitely, Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule is safe in lactation for baby. No wonder your doctor has recommended it.


If I am using Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule, will my baby need extra monitoring?

No extra baby monitoring required while mother is using Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule


Who can I talk to if I have questions about usage of Divalproex Sodium Delayed Release (sprinkle) | Divalproex Sodium Capsule in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week