Siklos | Hydroxyurea Tablet Breastfeeding
For most of the drugs advantages of taking medications overweighs the potential risks however some drugs could be really dangerous for breastfed baby hence every medication shall be considered separately. In this page we will discuss about purpose of Siklos | Hydroxyurea Tablet and its risk associated with lactation. We will also discuss the usage of Siklos | Hydroxyurea Tablet and some common side effects associated with Siklos | Hydroxyurea Tablet.

What is Siklos | Hydroxyurea Tablet used for?


SIKLOS® is indicated to reduce the frequency of painful crises and to reduce the need for blood transfusions in pediatric patients, 2 years of age and older, with sickle cell anemia with recurrent moderate to severe painful crises. SIKLOS is an antimetabolite, indicated to reduce the frequency of painful crises and to reduce the need for blood transfusions in pediatric patients, 2 years of age and older, with sickle cell anemia with recurrent moderate to severe painful crises.

I am breastfeeding mother and I am using Siklos | Hydroxyurea Tablet. Can it have any bad effect on my kid? Shall I search for better alternative?

Siklos | Hydroxyurea Tablet low risk for breastfeeding
Siklos | Hydroxyurea Tablet contains only one active ingredient that is Hydroxyurea. We have analyzed the usage of Hydroxyurea in breastfeeding and our analysis suggest that Hydroxyurea poses Low risk for infant while breastfeeding and hence Siklos | Hydroxyurea Tablet itself shall be considered Low risk item for breastfeeding.

Siklos | Hydroxyurea Tablet Breastfeeding Analsys


Hydroxyurea while Breastfeeding

Low Risk

CAS Number: 127-07-1

Used for the treatment of myeloproliferative disorders (polycythemia vera, essential thrombocythemia, myeloid leukemia, myeloid splenomegaly), certain cancers and prevention of recurrent painful occlusive crisis in sickle cell anemia from older than 2 years old . It is excreted in breast milk in small amounts, below 10% of relative adult dose or theoretical dose in pediatric patients, so it is not expected the occurrence of side effects on the breastfed infant whose mother is receiving this treatment. Risk may be lowered, especially in infants younger than 3 months, by delaying breastfeeding from 12 to 24 hours after dose.Whenever a long-term treatment is desired monitoring of blood count in the infant should be considered.

Siklos | Hydroxyurea Tablet Breastfeeding Analsys - 2


Hydroxyurea while Breastfeeding

CAS Number: 127-07-1

Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy, although the evidence for this recommendation is very weak.[1][2] Although only minimal data are available to determine an appropriate period to withhold breastfeeding, the drug's terminal half-live of 4.5 hours with normal kidney function suggests that withholding breastfeeding for at least 24 hours may be sufficient for patients receiving intermittent therapy. This period may be longer in patients with impaired kidney function. Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[3]

Is Siklos | Hydroxyurea Tablet safe while breastfeeding

What should I do if I am breastfeeding mother and I am already exposed to Siklos | Hydroxyurea Tablet?

Siklos | Hydroxyurea Tablet is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Siklos | Hydroxyurea Tablet so you should inform him based on your convenience.


I am nursing mother and my doctor has suggested me to use Siklos | Hydroxyurea Tablet, is it safe?

Though Siklos | Hydroxyurea Tablet dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Siklos | Hydroxyurea Tablet, will my baby need extra monitoring?

Not much monitoring required while using Siklos | Hydroxyurea Tablet


Who can I talk to if I have questions about usage of Siklos | Hydroxyurea Tablet in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week