Topcare Anti-itch | Diphenhydramine Hydrochloride And Zinc Acetate Cream while Breastfeeding

What is Topcare Anti-itch | Diphenhydramine Hydrochloride And Zinc Acetate Cream ?

Is using Topcare Anti-itch | Diphenhydramine Hydrochloride And Zinc Acetate Cream safe or dangerous while breastfeeding?

Diphenhydramine hydrochloride while Breastfeeding

CAS Number: 58-73-1

It is a first generation antihistamine drug (Ethanolamine) with a strong sedative effect. A high protein-binding capacity makes difficult an excretion into breast milk in significant amounts in accordance with old studies that had confirmed it. The absorption from ingested mother's milk to the infant's plasma is hampered by a low oral bioavailability. For both, the mother and the infant is safer the use of antihistamine medication with higher safety levels without sedative effect, especially when the child is a premature or younger than 1 month old. Neither a decrease of milk production nor alteration of Prolactin release have been shown with the use of this drug. When used while breastfeeding do it with the lower dose as possible and avoid a long-term use. Check up for feeding difficulty and somnolence in the infant. Bed-sharing with the infant is not recommended for parents who are on this medication.

Zinc acetate while Breastfeeding

CAS Number: 557-34-6

Zinc (Zn) is an essential element for nutrition. It is present in many foods.Recommended daily allowance of Zn is 8 to 15 mg. (Moran Hall 2010). Millions of people worldwide are Zn-deficient.It is used as a treatment for Wilson's disease and Acrodermatitis Enteropathica. Zn is involved in the regulation process of lactation (Lee 2016).Pasteurization of the milk does not affect the concentration of Zn and other trace elements (Mohd Taufek-2016). The average concentration of Zn in breastmilk is 4 to 16 mg / L (Picciano 1976, Hannan 2005, Dórea 2012) which is independent of plasma levels and maternal daily intake (Krebs 1995, Chierici 1999, Hannan 2009).Intestinal absorption of zinc is almost doubled during pregnancy and lactation (Fung 1997).Zinc levels in the infant are dependent on Zinc levels in the breast milk (Dumrongwongsiri 2015)With a varied and balanced diet, an extra intake of minerals is not needed. Excessive intake of Zinc may cause gastrointestinal problems and Pancytopenia (Irving 2003).

Diphenhydramine hydrochloride while Breastfeeding

CAS Number: 58-73-1

Small, occasional doses of diphenhydramine would not be expected to cause any adverse effects in breastfed infants. Larger doses or more prolonged use may cause effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established. Single bedtime doses after the last feeding of the day may be adequate for many women and will minimize any effects of the drug. The nonsedating antihistamines are preferred alternatives.

What if I already have used Topcare Anti-itch | Diphenhydramine Hydrochloride And Zinc Acetate Cream?

My doctor has prescribed me Topcare Anti-itch | Diphenhydramine Hydrochloride And Zinc Acetate Cream, what should I do?

If I am using Topcare Anti-itch | Diphenhydramine Hydrochloride And Zinc Acetate Cream, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Topcare Anti-itch | Diphenhydramine Hydrochloride And Zinc Acetate Cream in breastfeeding?