American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Macrodantin | Nitrofurantoin Macrocrystals Capsule for its safety in breastfeeding.
What is Macrodantin | Nitrofurantoin Macrocrystals Capsule used for?
Macrodantin is specifically indicated for the treatment of urinary tract infections when due to susceptible strains of Escherichia coli, enterococci, Staphylococcus aureus, and certain susceptible strains of Klebsiella and Enterobacter species. Nitrofurantoin is not indicated for the treatment of pyelonephritis or perinephric abscesses. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Macrodantin and other antibacterial drugs, Macrodantin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Nitrofurantoins lack the broader tissue distribution of other therapeutic agents approved for urinary tract infections. Consequently, many patients who are treated with Macrodantin are predisposed to persistence or reappearance of bacteriuria. Urine specimens for culture and susceptibility testing should be obtained before and after completion of therapy. If persistence or reappearance of bacteriuria occurs after treatment with Macrodantin, other therapeutic agents with broader tissue distribution should be selected. In considering the use of Macrodantin, lower eradication rates should be balanced against the increased potential for systemic toxicity and for the development of antimicrobial resistance when agents with broader tissue distribution are utilized.
Is using Macrodantin | Nitrofurantoin Macrocrystals Capsule unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?
Active ingredient in Macrodantin | Nitrofurantoin Macrocrystals Capsule is Nitrofurantoin and based on our analysis of Nitrofurantoin it appears that using Macrodantin | Nitrofurantoin Macrocrystals Capsule is safe in breastfeeding. Below is analysis of Nitrofurantoin while breastfeeding.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Nitrofurantoin has been detected in human breast milk in trace amounts. Because of the potential for serious adverse reactions from nitrofurantoin in nursing infants under one month of age, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother (see CONTRAINDICATIONS ).
Macrodantin | Nitrofurantoin Macrocrystals Capsule Breastfeeding Analsys
SafeCAS Number: 67-20-9
Excretion into breast milk is clinically non-significant with no side-effects observed among breastfed infants from treated mothers except rare cases of diarrhea. Do not use while the infant is younger of two weeks of age or suffers of G-6-P dehydrogenase deficiency to avoid likelihood of hemolysis. Be aware of false negative results that may be obtained from febrile infants with bacterial cultures when the mother is on antibiotics. Also, the possibility of developing diarrhea due to bacterial flora imbalance.
Macrodantin | Nitrofurantoin Macrocrystals Capsule Breastfeeding Analsys - 2
CAS Number: 67-20-9
Administration of nitrofurantoin directly to infants under 1 month of age and in those with glucose-6-phosphate dehydrogenase (G6PD) deficiency is contraindicated because of potential hemolysis in these infants. However, the time of greatest risk for hemolysis in fullterm newborns without G6PD deficiency might be as short as 8 days after birth.[1] Nitrofurantoin doses in milk are low and it can be used while breastfeeding older infants, but alternate drugs are preferred in mothers of infants under 8 days of age, or infants with G6PD deficiency of any age. Observe infants for possible diarrhea.
I already used Macrodantin | Nitrofurantoin Macrocrystals Capsule and meanwhile I breastfed my baby should I be concerned?
As usage of Macrodantin | Nitrofurantoin Macrocrystals Capsule is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Macrodantin | Nitrofurantoin Macrocrystals Capsule else no further action is required.
My health care provider has asked me to use Macrodantin | Nitrofurantoin Macrocrystals Capsule, what to do?
Definitely, Macrodantin | Nitrofurantoin Macrocrystals Capsule is safe in lactation for baby. No wonder your doctor has recommended it.
If I am using Macrodantin | Nitrofurantoin Macrocrystals Capsule, will my baby need extra monitoring?
No extra baby monitoring required while mother is using Macrodantin | Nitrofurantoin Macrocrystals Capsule
Who can I talk to if I have questions about usage of Macrodantin | Nitrofurantoin Macrocrystals Capsule in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week
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