It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Propofol Injectable Emulsion Injection, Emulsion is safe for baby while breastfed.
What is Propofol Injectable Emulsion Injection, Emulsion used for?
Propofol injectable emulsion, USP is an IV general anesthetic and sedation drug that can be used as described in the table below.. T able 3. Indications for Propofol Injectable Emulsion, USP I nd ication Approved Patient Population Initiation and maintenance of Monitored Adults only Anesthesia Care (MAC) sedation Combined sedation and regional anesthesia Adults only (see PRECAUTIONS) Induction of General Anesthesia Maintenance of General Anesthesia Patients greater than or equal to 3 years of age Patients greater than or equal to 2 months of age Intensive Care Unit (ICU) sedation of intubated, mechanically ventilated patients Adults only Safety, effectiveness and dosing guidelines for propofol injectable emulsion, USP have not been established for MAC Sedation in the pediatric population; therefore, it is not recommended for this use (see PRECAUTIONS, Pediatric Use). Propofol injectable emulsion, USP is not recommended for induction of anesthesia below the age of 3 years or for maintenance of anesthesia below the age of 2 months because its safety and effectiveness have not been established in those populations. In the Intensive Care Unit (ICU), propofol injectable emulsion, USP can be administered to intubated, mechanically ventilated adult patients to provide continuous sedation and control of stress responses only by persons skilled in the medical management of critically ill patients and trained in cardiovascular resuscitation and airway management. Propofol injectable emulsion, USP is not indicated for use in Pediatric ICU sedation since the safety of this regimen has not been established (see PRECAUTIONS, Pediatric Use). Propofol injectable emulsion, USP is not recommended for obstetrics, including Cesarean section deliveries. Propofol injectable emulsion, USP crosses the placenta, and as with other general anesthetic agents, the administration of propofol injectable emulsion, USP may be associated with neonatal depression (see PRECAUTIONS). Propofol injectable emulsion, USP is not recommended for use in nursing mothers because propofol has been reported to be excreted in human milk, and the effects of oral absorption of small amounts of propofol, USP are not known (see PRECAUTIONS).
Is using Propofol Injectable Emulsion Injection, Emulsion unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?
Active ingredient in Propofol Injectable Emulsion Injection, Emulsion is Propofol and based on our analysis of Propofol it appears that using Propofol Injectable Emulsion Injection, Emulsion is safe in breastfeeding. Below is analysis of Propofol while breastfeeding.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Nursing Mothers Propofol injectable emulsion is not recommended for use in nursing mothers because propofol injectable emulsion has been reported to be excreted in human milk and the effects of oral absorption of small amounts of propofol are not known.
Propofol Injectable Emulsion Injection, Emulsion Breastfeeding Analsys
SafeCAS Number: 2078-54-8
Because of a high protein-binding capacity and a high volume of distribution, excretion into the breast milk is non-significant. No side-effects were observed in breastfed infants of mothers who were administered this medication. The nursing mother may breastfeed the baby as soon as she is recovered from anesthesia. A transient increase in Prolactin plasma levels has been observed with Propofol anesthesia. A case of green-bluish discoloration of the milk has been reported after administration of Propofol plus other drugs. Authorized medication for use in infants older than 1 month.
Propofol Injectable Emulsion Injection, Emulsion Breastfeeding Analsys - 2
CAS Number: 2078-54-8
Amounts of propofol in milk are very small and are not expected to be absorbed by the infant. Although one expert panel recommends withholding nursing for an unspecified time after propofol administration,[1] most recommend that breastfeeding can be resumed as soon as the mother has recovered sufficiently from general anesthesia to nurse and that discarding milk is unnecessary.[2][3][4] When a combination of anesthetic agents is used for a procedure, follow the recommendations for the most problematic medication used during the procedure. General anesthesia for cesarean section using propofol as a component for induction may delay the onset of lactation. In one study, breastfeeding before general anesthesia induction reduced requirements of propofol and sevoflurane compared to those of nursing mothers whose breastfeeding was withheld or nonnursing women.[5] In one case, milk was noted to be green in color 8 hours after a procedure in which propofol was administered; however, several other medications were also used during the procedure.
What should I do if already breastfed my kid after using Propofol Injectable Emulsion Injection, Emulsion?
Propofol Injectable Emulsion Injection, Emulsion is safe in breastfeeding and should not create any health problem for your baby but in case you feel any health issue associated with Propofol Injectable Emulsion Injection, Emulsion you should contact your doctor or health care provider. Be it pregnancy or lactation you shall keep your doctor informed.
My health care provider has asked me to use Propofol Injectable Emulsion Injection, Emulsion, what to do?
Definitely, Propofol Injectable Emulsion Injection, Emulsion is safe in lactation for baby. No wonder your doctor has recommended it.
If I am using Propofol Injectable Emulsion Injection, Emulsion, will my baby need extra monitoring?
No extra baby monitoring required while mother is using Propofol Injectable Emulsion Injection, Emulsion
Who can I talk to if I have questions about usage of Propofol Injectable Emulsion Injection, Emulsion in breastfeeding?
US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week